Navigating in vitro bioactivity data by investigating available resources using model compounds

Sten Ilmjärv; Fiona Augsburger; Jerven Tjalling Bolleman; Robin Liechti; Alan James Bridge; Jenny Sandström; Vincent Jaquet; Ioannis Xenarios; Karl-Heinz Krause

doi:10.1038/s41597-019-0046-1

Navigating in vitro bioactivity data by investigating available resources using model compounds

Sci Data. 2019 Apr 29;6(1):45. doi: 10.1038/s41597-019-0046-1.

Authors

Sten Ilmjärv^{1

2}, Fiona Augsburger³, Jerven Tjalling Bolleman⁴, Robin Liechti⁵, Alan James Bridge⁴, Jenny Sandström⁶, Vincent Jaquet³, Ioannis Xenarios^{5

7

8}, Karl-Heinz Krause⁹

Affiliations

¹ Department of Pathology and Immunology, Medical School, University of Geneva, Geneva, Switzerland. sten.ilmjarv@unige.ch.
² Vital-IT Group, SIB Swiss Institute of Bioinformatics, Lausanne, Switzerland. sten.ilmjarv@unige.ch.
³ Department of Pathology and Immunology, Medical School, University of Geneva, Geneva, Switzerland.
⁴ Swiss-Prot group, SIB Swiss Institute of Bioinformatics, Medical School, Geneva, Switzerland.
⁵ Vital-IT Group, SIB Swiss Institute of Bioinformatics, Lausanne, Switzerland.
⁶ SCAHT Swiss Centre for Applied Human Toxicology, Basel, Switzerland.
⁷ Center for Integrative Genomics, University of Lausanne, Lausanne, Switzerland.
⁸ Departement of Biochemistry and Chemistry, University of Geneva, Geneva, Switzerland.
⁹ Department of Pathology and Immunology, Medical School, University of Geneva, Geneva, Switzerland. karl-heinz.krause@unige.ch.

Abstract

The number of chemical compounds and associated experimental data in public databases is growing, but presently there is no simple way to access these data in a quick and synoptic manner. Instead, data are fragmented across different resources and interested parties need to invest invaluable time and effort to navigate these systems.

Publication types

Research Support, Non-U.S. Gov't