This is a review of percutaneous vertebroplasty (PVP), which has been performed since the 1980s. Initially, PVP was for palliative treatment of malignant lesions in columna, and later it was for osteoporotic fractures. According to hundreds of studies, PVP has had great pain reductive effect com-pared to conservative treatment i.e. analgesics. Traditionally, the procedure has been offered to patients with persistent pain despite a period of conservative treatment. New re-search suggests, that PVP has the best effect if completed within six weeks of pain debut.