Effect of teduglutide on restoring oral autonomy for magnesium in two patients with short bowel

Nutrition. 2019 Sep:65:13-17. doi: 10.1016/j.nut.2019.02.014. Epub 2019 Feb 27.

Abstract

It is not known whether Teduglutide can allow patients with Short bowel syndrome, previously dependent on continuous or periodic intravenous (IV) magnesium, to attain oral autonomy with or without supplementation. Here, we report on two patients previously dependent on continuous or intermittently administered IV magnesium to achieve autonomy from IV, one with and one without oral supplementation that was previously ineffective in both patients.

Keywords: Balance; Hypomagnesemia; Jejunostomy; Magnesium; Malabsorption; Short bowel; Teduglutide.

Publication types

  • Case Reports
  • Research Support, Non-U.S. Gov't

MeSH terms

  • Aged
  • Dietary Supplements
  • Female
  • Gastrointestinal Agents / therapeutic use*
  • Humans
  • Intestinal Absorption
  • Magnesium / administration & dosage*
  • Magnesium Deficiency / drug therapy*
  • Magnesium Deficiency / etiology
  • Magnesium Deficiency / physiopathology
  • Middle Aged
  • Nutritional Status
  • Peptides / therapeutic use*
  • Short Bowel Syndrome / complications
  • Short Bowel Syndrome / drug therapy*
  • Short Bowel Syndrome / physiopathology
  • Treatment Outcome

Substances

  • Gastrointestinal Agents
  • Peptides
  • teduglutide
  • Magnesium