Supramolecular-based nanofibers

Yi Wang; Joshua Chou; Yulong Sun; Shizhu Wen; Steven Vasilescu; Hongyu Zhang

doi:10.1016/j.msec.2019.04.021

Supramolecular-based nanofibers

Mater Sci Eng C Mater Biol Appl. 2019 Aug:101:650-659. doi: 10.1016/j.msec.2019.04.021. Epub 2019 Apr 9.

Authors

Yi Wang¹, Joshua Chou², Yulong Sun¹, Shizhu Wen¹, Steven Vasilescu³, Hongyu Zhang⁴

Affiliations

¹ State Key Laboratory of Tribology, Department of Mechanical Engineering, Tsinghua University, Beijing 100084, China.
² School of Biomedical Engineering, University of Technology Sydney, P. O. Box 123, NSW 2007, Australia.
³ School of Mathematical and Physical Science, Faculty of Science, University of Technology Sydney, P. O. Box 123, NSW 2007, Australia.
⁴ State Key Laboratory of Tribology, Department of Mechanical Engineering, Tsinghua University, Beijing 100084, China. Electronic address: zhanghyu@tsinghua.edu.cn.

PMID: 31029359
DOI: 10.1016/j.msec.2019.04.021

Abstract

Supramolecular-based nanofibers, which successfully combine the unique properties of supramolecular interactions with the advantages of nanofibrous structure, are widely used in a variety of biomedical applications such as controlled drug delivery. Compared with traditional polymer nanofibers, supramolecular-based nanofibers can overcome the bottleneck of sensitivity because of the non-covalent binding modes, and therefore match the requirements of rapid and reversible response to the external stimuli. In addition, supramolecular-based nanofibers can achieve extra controllable and dynamic responsive (e.g. pH, temperature) functions in different environments. In this review, we retrospected and summarized the recent development of supramolecular-based nanofibers, focusing particularly on electrospun supramolecular nanofibers, while also touching on the advances of directly self-assembled supramolecular nanofibers without the use of electrospinning. Furthermore, we discussed the potential biomedical applications of supramolecular nanofibers. Finally, this review was concluded by elaborating upon individual reflection on the current situation, forecasting the future trend of this promising material.

Keywords: Electrospun; Inclusion complex; Nanofibers; Self-assembly; Supramolecular interaction.

Publication types

Review

MeSH terms

Biocompatible Materials / chemistry*
Drug Delivery Systems / methods*
Hydrogen-Ion Concentration
Nanofibers / chemistry*
Temperature
Tissue Engineering / methods

Substances

Biocompatible Materials