Influence of Sialadenectomy on the Development of Spermatogenesis in Rats: Ultrastructural Characteristics of Spermatogenic Epithelium and Leydig Cells

V V Ivanova; I V Mil'to; I V Sukhodolo; V Yu Usov

doi:10.1007/s10517-019-04444-w

Influence of Sialadenectomy on the Development of Spermatogenesis in Rats: Ultrastructural Characteristics of Spermatogenic Epithelium and Leydig Cells

Bull Exp Biol Med. 2019 Apr;166(6):802-805. doi: 10.1007/s10517-019-04444-w. Epub 2019 Apr 26.

Authors

V V Ivanova¹, I V Mil'to², I V Sukhodolo², V Yu Usov³

Affiliations

¹ Department of Morphology and General Pathology, Siberian State Medical University, Ministry of Health of the Russian Federation, Tomsk, Russia. ivvera92@rambler.ru.
² Department of Morphology and General Pathology, Siberian State Medical University, Ministry of Health of the Russian Federation, Tomsk, Russia.
³ Department of X-Ray and Tomographic Diagnostic Methods, Research Institute of Cardiology, Tomsk National Research Medical Center, Russian Academy of Sciences, Tomsk, Russia.

PMID: 31028585
DOI: 10.1007/s10517-019-04444-w

Abstract

Sialadenectomy in young rats modifies the development of the spermatogenic and steroidogenic functions of the testes. Sialadenectomy causes ultrastructural changes in spermatogenic cells, sustentocytes, and Leydig cells that disappear by week 8 of the experiment due to realization of compensatory and adaptive mechanisms. The effects of endocrine factors of the greater salivary glands on the spermatogenic cells are realized directly and indirectly via interstitial endocrinocytes and sustentocytes.

Keywords: Leydig cells; sialadenectomy; spermatogenic cells; sustentocytes.

MeSH terms

Adaptation, Physiological
Animals
Animals, Outbred Strains
Leydig Cells / ultrastructure*
Male
Rats
Salivary Glands / physiology
Salivary Glands / surgery*
Seminiferous Epithelium / ultrastructure*
Sertoli Cells / ultrastructure*
Spermatogenesis / physiology
Time Factors