A case of metastatic dysgerminoma treated with two cycles neoadjuvant chemotherapy followed by fertility-sparing minimally invasive surgery

Katrin E Eurich; Elizabeth Swisher; Mirna Toukatly; Lisa Koch; Emily S Wu

doi:10.1016/j.gore.2019.04.003

A case of metastatic dysgerminoma treated with two cycles neoadjuvant chemotherapy followed by fertility-sparing minimally invasive surgery

Gynecol Oncol Rep. 2019 Apr 6:28:124-127. doi: 10.1016/j.gore.2019.04.003. eCollection 2019 May.

Authors

Katrin E Eurich¹, Elizabeth Swisher¹, Mirna Toukatly², Lisa Koch², Emily S Wu¹

Affiliations

¹ Division of Gynecologic Oncology, Department of Obstetrics and Gynecology, University of Washington, 1959 NE Pacific Street, Box 356460, Seattle, WA 98195, USA.
² Department of Pathology, University of Washington, 1959 NE Pacific Street, Box 357470, Seattle, WA 98195, USA.

Abstract

•Neoadjuvant chemotherapy (NACT) followed by fertility-sparing surgery is a feasible treatment of metastatic dysgerminoma•As few as two cycles of NACT may result in enough of a tumor response for fertility-sparing surgery to be possible.•Tumor lysis syndrome is a possibility when administering chemotherapy to patients with metastatic dysgerminoma.

Keywords: Dysgerminoma; Fertility-sparing surgery; Neoadjuvant chemotherapy.

Publication types

Case Reports