Inhaled Cisplatin for NSCLC: Facts and Results

Int J Mol Sci. 2019 Apr 24;20(8):2005. doi: 10.3390/ijms20082005.

Abstract

Although we have new diagnostic tools for non-small cell lung cancer, diagnosis is still made in advanced stages of the disease. However, novel treatments are being introduced in the market and new ones are being developed. Targeted therapies and immunotherapy have brought about a bloom in the treatment of non-small cell lung cancer. Still we have to find ways to administer drugs in a more efficient and safe method. In the current review, we will focus on the administration of inhaled cisplatin based on published data.

Keywords: NSCLC; cisplatin; inhalation; lung cancer; nebulizers.

Publication types

  • Review

MeSH terms

  • Administration, Inhalation
  • Animals
  • Antineoplastic Agents / administration & dosage*
  • Antineoplastic Agents / pharmacokinetics
  • Antineoplastic Agents / therapeutic use
  • Biological Availability
  • Carcinoma, Non-Small-Cell Lung / drug therapy*
  • Cisplatin / administration & dosage*
  • Cisplatin / pharmacokinetics
  • Cisplatin / therapeutic use
  • Humans
  • Lung / drug effects
  • Lung Neoplasms / drug therapy*
  • Nebulizers and Vaporizers

Substances

  • Antineoplastic Agents
  • Cisplatin