Abstract
Amyloidosis and lymphoma localized to the ocular adnexa are rare, and their presentation may resemble more common inflammatory conditions such as autoimmune disease or infection, which can protract diagnostic evaluation and delay eventual therapy. In a patient with recalcitrant facial and tooth pain and ophthalmoplegia, evaluation should include careful histopathologic analysis of biopsy specimens. We report a case of orbital AL amyloidosis associated with localized lymphoma that presented with intractable dental pain and progressed to bilateral complete ophthalmoplegia.
Keywords:
Amyloidosis; facial pain; lymphoma; ophthalmoplegia; osteomyelitis.
MeSH terms
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Biopsy, Needle
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Blepharoptosis / diagnosis
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Blepharoptosis / etiology
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Diplopia / diagnosis
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Diplopia / etiology
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Disease Progression
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Female
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Follow-Up Studies
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Humans
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Immunoglobulin Light-chain Amyloidosis / diagnostic imaging
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Immunoglobulin Light-chain Amyloidosis / pathology*
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Immunoglobulin Light-chain Amyloidosis / surgery
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Immunohistochemistry
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Lymphoma / diagnostic imaging
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Lymphoma / pathology*
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Lymphoma / surgery*
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Magnetic Resonance Imaging / methods
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Middle Aged
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Ophthalmoplegia / diagnosis
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Ophthalmoplegia / etiology
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Orbital Diseases / diagnostic imaging
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Orbital Diseases / pathology*
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Orbital Diseases / surgery*
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Rare Diseases
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Risk Assessment
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Toothache / diagnosis
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Toothache / etiology
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Treatment Outcome