Create Nanoscale Patterns with DNA Origami

Sisi Fan; Dongfang Wang; Ahmad Kenaan; Jin Cheng; Daxiang Cui; Jie Song

doi:10.1002/smll.201805554

Create Nanoscale Patterns with DNA Origami

Small. 2019 Jun;15(26):e1805554. doi: 10.1002/smll.201805554. Epub 2019 Apr 24.

Authors

Sisi Fan¹, Dongfang Wang¹, Ahmad Kenaan¹, Jin Cheng¹, Daxiang Cui¹, Jie Song^{1

2}

Affiliations

¹ Institute of Nano Biomedicine and Engineering, Department of Instrument Science and Engineering, School of Electronic Information and Electrical Engineering, Shanghai Jiao Tong University, Shanghai, 200240, China.
² Shanghai Engineering Research Center of Advanced Dental Technology and Materials, Shanghai Ninth People's Hospital, Shanghai Jiao Tong University, Shanghai, 200011, China.

PMID: 31018040
DOI: 10.1002/smll.201805554

Abstract

Structural deoxyribonucleic acid (DNA) nanotechnology offers a robust platform for diverse nanoscale shapes that can be used in various applications. Among a wide variety of DNA assembly strategies, DNA origami is the most robust one in constructing custom nanoshapes and exquisite patterns. In this account, the static structural and functional patterns assembled on DNA origami are reviewed, as well as the reconfigurable assembled architectures regulated through dynamic DNA nanotechnology. The fast progress of dynamic DNA origami nanotechnology facilitates the construction of reconfigurable patterns, which can further be used in many applications such as optical/plasmonic sensors, nanophotonic devices, and nanorobotics for numerous different tasks.

Keywords: DNA origami; reconfigurable patterns; static patterns.

Publication types

Research Support, Non-U.S. Gov't
Review

MeSH terms

DNA / chemistry*
Nanostructures / chemistry*
Nanotechnology / methods*

Substances

DNA