In dioecious species, sex-related adaptive strategies, influenced by natural and sexual selection, allow each sex to meet the specific demands of reproduction. Differences in ecophysiological traits between males and females may rely on innate differences in secondary sex traits such as structural and functional leaf traits. We tested structural sexual leaf dimorphism in Pistacia vera L. and the intersexual differences in sun-shade acclimation processes expected from the different adaptive strategies of males and females. Fifteen structural and functional leaf traits were compared in 50-year-old trees between females with low fruit load and males under sun and shade conditions. Despite the low additional energy investment in reproduction in females, remarkable sex effects in leaf structure and function were observed. Male trees had smaller leaves with significantly lower total conducting petiole area (TCA) and higher stomatal density, water use efficiency and concentration of phenolic compounds; females had larger leaves with greater thickness, leaf mass per area, TCA and maximum photosynthetic capacity per area (Amax,a). The higher Amax,a and stomatal conductance of female leaves were associated with their ~20-fold higher TCA compared with male trees. Females seem to invest more in high xylem efficiency and rates of C gain; males invest more in defence-protection. Sun-shade plastic responses were sex- and trait-specific, but the plasticity assessment indicated that both sexes have evolved an almost equal degree of phenotypic plasticity that allows them to perform optimally under varying environmental conditions. However, the trait-specific differences indicate that each sex displays a different strategy of optimisation.