Recruitment and participant baseline characteristics in the dialysis outcomes in those aged 65 years or older study

Bronwen McNoe; John B W Schollum; Sarah Derrett; Mark R Marshall; Andrew Henderson; Ari Samaranayaka; Robert J Walker

doi:10.1186/s12882-019-1328-8

Recruitment and participant baseline characteristics in the dialysis outcomes in those aged 65 years or older study

BMC Nephrol. 2019 Apr 23;20(1):137. doi: 10.1186/s12882-019-1328-8.

Authors

Bronwen McNoe¹, John B W Schollum², Sarah Derrett¹, Mark R Marshall³, Andrew Henderson⁴, Ari Samaranayaka⁵, Robert J Walker⁶

Affiliations

¹ Department of Preventive and Social Medicine, University of Otago, PO Box 56, Dunedin, 9054, New Zealand.
² Department of Medicine, University of Otago, Dunedin, New Zealand.
³ Department of Renal Medicine, Middlemore Hospital, Counties Manukau District Health Board, Manukau, New Zealand.
⁴ Renal Medicine, Hamilton Hospital, Waikato District Health Board, Hamilton, New Zealand.
⁵ Biostatistics unit, University of Otago, Dunedin, New Zealand.
⁶ Department of Medicine, University of Otago, Dunedin, New Zealand. rob.walker@otago.ac.nz.

Abstract

Background: Despite an increasing number of older people commencing dialysis the impact of dialysis on their quality of life and survival, remains unclear. The Dialysis Outcomes in those aged over 65 years or older study is an accelerated prospective cohort longitudinal design study, designed to obtain sufficient health related quality of life data, linked to clinical data, to inform clinicians' and patients' decision-making with respect to end stage kidney disease (ESKD), outcomes, and options for management in New Zealand (NZ).

Methods: The study has an accelerated prospective cohort longitudinal design, comprised of cross-sectional and longitudinal components. We report the baseline data on the 225 participants enrolled in the study. Dialysis duration was grouped in tertiles from less than one year (incident patients), 1-3 years and greater than 3 years. Health related quality of life data was obtained from self-reported questionnaires including KDQoL-36, EQ-5D-3 L, FACIT, WHODAS II, and the Personal Well-being Score.

Results: The median age of the cohort was 71 years and two thirds were male. Three quarters of the participants were on dialysis at the baseline, with 42% of those on home dialysis (haemodialysis or peritoneal dialysis). Māori and Pacific people were over represented (20% Māori and 24% Pacific) in the sample, when compared to the general NZ population of the same age group (where 5% are Māori and 2% are Pacific). At baseline, there were no differences observed in sociodemographic, quality of life or health characteristics between the dialysis groups either by modality or duration of dialysis.

Conclusions: We report the baseline characteristics of participants enrolled prospectively into a longitudinal cohort observational study examining health related quality of life factors with clinical characteristics on dialysis outcomes in a group of New Zealanders aged 65 years or older who are either on dialysis or have been educated about dialysis (BMC Nephrol 14:175, 2013). Subsequent publications are planned, analysing the prospective longitudinal data to identify key factors that determine both outcome and quality of life for individuals of this age group.

Trial registration: ACTRN12611000024943 .

Keywords: Comorbidities; Dialysis; Elderly; Quality of life.

Publication types

Research Support, Non-U.S. Gov't

MeSH terms

Aged
Female
Humans
Kidney Failure, Chronic* / epidemiology
Kidney Failure, Chronic* / psychology
Kidney Failure, Chronic* / therapy
Longitudinal Studies
Male
New Zealand / epidemiology
Patient Outcome Assessment
Patient Selection*
Quality of Life*
Renal Dialysis* / methods
Renal Dialysis* / psychology
Renal Dialysis* / statistics & numerical data
Surveys and Questionnaires

Associated data

ANZCTR/ACTRN12611000024943