Cardiac Implantable Electronic Device-Related Infection Due to Granulicatella adiacens

Parham Sendi; Kerstin Wustmann; Annina E Büchi; Fabian Noti; Bernd Klaeser; Beat Sonderegger; Christoph Auf der Maur; Thomas Mercier; Markus Schwerzmann; Corinne Ruppen

doi:10.1093/ofid/ofz130

Cardiac Implantable Electronic Device-Related Infection Due to Granulicatella adiacens

Open Forum Infect Dis. 2019 Mar 14;6(4):ofz130. doi: 10.1093/ofid/ofz130. eCollection 2019 Apr.

Authors

Parham Sendi^{1

2}, Kerstin Wustmann^{3

4}, Annina E Büchi⁵, Fabian Noti⁴, Bernd Klaeser⁶, Beat Sonderegger⁷, Christoph Auf der Maur⁸, Thomas Mercier⁹, Markus Schwerzmann^{3

4}, Corinne Ruppen¹

Affiliations

¹ Institute for Infectious Diseases, University of Bern.
² Department of Infectious Diseases, University of Bern.
³ Center for Congenital Heart Disease, Inselspital, University Hospital Bern, University of Bern.
⁴ Department of Cardiology, Inselspital, University Hospital Bern, University of Bern.
⁵ Department of General Internal Medicine, Inselspital, University Hospital Bern, University of Bern.
⁶ Department of Nuclear Medicine, Inselspital, University Hospital Bern, University of Bern.
⁷ Department of Infectious Diseases and Hospital Epidemiology, Lausanne University Hospital and University of Lausanne, Switzerland.
⁸ Paediatric and Adult Cardiology, Kantonsspital Lucerne, Lausanne University Hospital and University of Lausanne, Switzerland.
⁹ Service and Laboratory of Clinical Pharmacology, Department of Laboratories, Lausanne University Hospital and University of Lausanne, Switzerland.

Abstract

Cardiac implantable electronic device-related infection is clinically challenging. Curative treatment commonly includes system removal. A case caused by Granulicatella adiacens occurred in a 32-year-old woman. Clinical course, literature review, and biofilm investigations enabled successful antibiotic management without system removal.

Keywords: Granulicatella adiacens; biofilm infection; cardiac device-related infection; endocarditis; nutritionally variant streptococci.