Eremothecium coryli bloodstream infection in a patient with acute myeloid leukemia: first case report of human infection

Ashrit Multani; Arjun Rustagi; David J Epstein; Carlos A Gomez; Indre Budvytiene; Niaz Banaei; Janice M Brown; Anne Y Liu

doi:10.1016/j.diagmicrobio.2019.03.011

Eremothecium coryli bloodstream infection in a patient with acute myeloid leukemia: first case report of human infection

Diagn Microbiol Infect Dis. 2019 Sep;95(1):77-79. doi: 10.1016/j.diagmicrobio.2019.03.011. Epub 2019 Mar 27.

Authors

Ashrit Multani¹, Arjun Rustagi², David J Epstein², Carlos A Gomez³, Indre Budvytiene⁴, Niaz Banaei⁵, Janice M Brown², Anne Y Liu²

Affiliations

¹ Division of Infectious Diseases and Geographic Medicine, Department of Medicine, Stanford University School of Medicine, Stanford, CA, USA. Electronic address: amultani@stanford.edu.
² Division of Infectious Diseases and Geographic Medicine, Department of Medicine, Stanford University School of Medicine, Stanford, CA, USA.
³ Division of Infectious Diseases, Department of Medicine, University of Utah School of Medicine, Salt Lake City, UT, USA.
⁴ Clinical Microbiology Laboratory, Stanford University Medical Center, Palo Alto, CA, USA.
⁵ Division of Infectious Diseases and Geographic Medicine, Department of Medicine, Stanford University School of Medicine, Stanford, CA, USA; Clinical Microbiology Laboratory, Stanford University Medical Center, Palo Alto, CA, USA; Department of Pathology, Stanford University School of Medicine, Stanford, CA, USA.

PMID: 31005402
DOI: 10.1016/j.diagmicrobio.2019.03.011

Abstract

Eremothecium coryli is a dimorphic fungus of the Saccharomycetes class. While species within this class are known to cause human infection, Eremothecium species have previously only been known as phytopathogens and never been isolated from a human sample. Here, we report the first known case of human E. coryli infection.

Keywords: 28S rRNA sequencing; Eremothecium coryli; Fungal infection; Fungal sequencing; Fungemia; Saccharomyces.

Publication types

Case Reports

MeSH terms

Antifungal Agents / pharmacology
Antifungal Agents / therapeutic use
Blood Culture
DNA, Fungal / genetics
Eremothecium / cytology
Eremothecium / drug effects
Eremothecium / genetics
Eremothecium / physiology*
Female
Fungemia / diagnosis*
Fungemia / drug therapy*
Fungemia / microbiology
Fungemia / pathology
Humans
Leukemia, Myeloid, Acute / complications*
Microbial Sensitivity Tests
RNA, Ribosomal, 28S / genetics
Sequence Analysis, DNA
Treatment Failure

Substances

Antifungal Agents
DNA, Fungal
RNA, Ribosomal, 28S