A Common Receptor Found for Echoviruses

Mira Laajala; Varpu Marjomäki

doi:10.1016/j.tim.2019.03.010

A Common Receptor Found for Echoviruses

Trends Microbiol. 2019 Jun;27(6):475-477. doi: 10.1016/j.tim.2019.03.010. Epub 2019 Apr 16.

Authors

Mira Laajala¹, Varpu Marjomäki²

Affiliations

¹ Department of Biological and Environmental Science, Nanoscience Center, University of Jyväskylä, PO, Box 35, FI-40014 Jyväskylä, Finland.
² Department of Biological and Environmental Science, Nanoscience Center, University of Jyväskylä, PO, Box 35, FI-40014 Jyväskylä, Finland. Electronic address: varpu.s.marjomaki@jyu.fi.

PMID: 31003872
DOI: 10.1016/j.tim.2019.03.010

Abstract

It has remained a puzzle why infants, during the first weeks of life, are especially prone to enterovirus infections. New work (Proc. Natl. Acad. Sci. U. S. A. 2019;116: 3758-3763) shines light on this matter by showing that the neonatal Fc receptor, prevalent in several tissues, acts as a pan receptor for several echoviruses.

Keywords: Echovirus infections; Fc receptor; enteroviruses; neonates.

Publication types

Comment

MeSH terms

Enterovirus B, Human*
Enterovirus Infections*
Histocompatibility Antigens Class I
Humans
Infant
Receptors, Fc

Substances

Histocompatibility Antigens Class I
Receptors, Fc
Fc receptor, neonatal