Impact of body mass index on post-thyroidectomy morbidity

Head Neck. 2019 Sep;41(9):2952-2959. doi: 10.1002/hed.25773. Epub 2019 Apr 19.

Abstract

Background: The impact of obesity on total thyroidectomy (TT) morbidity (recurrent laryngeal nerve palsy and hypocalcaemia) remains largely unknown.

Methods: In a prospective study (NCT01551914), patients were divided into five groups according to their body mass index (BMI): underweight, normal weight, overweight, obese, and severely obese. Preoperative and postoperative serum calcium was measured. Recurrent laryngeal nerve (RLN) function was evaluated before discharge, and if abnormal, at 6 months.

Results: In total 1310 patients were included. Baseline characteristics were similar across BMI groups except for age and sex. Postoperative hypocalcaemia was more frequent in underweight compared to obese patients but the difference was not statistically significant in multivariate analysis. There was no difference between groups in terms of definitive hypocalcaemia, transient and definitive RLN palsy, and postoperative pain.

Conclusion: Obesity does not increase intraoperative and postoperative morbidity of TT, despite a longer duration of the procedure.

Keywords: body mass index; obesity; postoperative complications; recurrent laryngeal nerve palsy; total thyroidectomy.

Publication types

  • Research Support, Non-U.S. Gov't

MeSH terms

  • Adult
  • Body Mass Index*
  • Calcium / blood
  • Female
  • Humans
  • Hypocalcemia / epidemiology
  • Length of Stay / statistics & numerical data
  • Male
  • Middle Aged
  • Operative Time
  • Pain, Postoperative / epidemiology
  • Postoperative Complications
  • Prospective Studies
  • Thyroidectomy / adverse effects*
  • Vocal Cord Paralysis / epidemiology

Substances

  • Calcium