We prospectively examined the effectiveness of diagnostic tests for anaplasmosis using patients with suspected diagnoses in France. PCR (sensitivity 0.74, specificity 1) was the best-suited test. Serology had a lower specificity but higher sensitivity when testing acute and convalescent samples. PCR and serology should be used in combination for anaplasmosis diagnosis.
Keywords: Anaplasma phagocytophilum; France; HGA; PCR; anaplasmosis; bacteria; blood smears; diagnosis; diagnostics; human granulocytic anaplasmosis; prospective study; serology; tickborne diseases; vector-borne infections.