Nivolumab and immune-mediated colitis

Clin Case Rep. 2019 Feb 19;7(4):644-647. doi: 10.1002/ccr3.2027. eCollection 2019 Apr.

Abstract

Nivolumab is associated with a number of immune-regulated adverse events, including immune-mediated colitis and may present following the discontinuation of treatment. Current guidance suggests lower doses of methylprednisolone; however, we described faster resolution of the patient's symptoms compared to previous reported cases, using higher dosing, thereby minimizing hospitalization.

Keywords: Nivolumab; PD‐1 receptor; immune‐mediated colitis; immune‐regulated adverse events.

Publication types

  • Case Reports