Highly Oxidized Graphene Quantum Dots from Coal as Efficient Antioxidants

ACS Appl Mater Interfaces. 2019 May 8;11(18):16815-16821. doi: 10.1021/acsami.9b01082. Epub 2019 Apr 26.

Abstract

Graphene quantum dots (GQDs) have recently been employed in various fields including medicine as antioxidants, primarily because of favorable biocompatibility in comparison to common inorganic quantum dots, although the structural features that lead to the biological activities of GQDs are poorly understood. Here, we report that coal-derived GQDs and their poly(ethylene glycol)-functionalized derivatives serve as efficient antioxidants, and we evaluate their electrochemical, chemical, and in vitro biological activities.

Keywords: antioxidant; carbon nanotechnology; coal; graphene quantum dots; superoxide dismutase.

MeSH terms

  • Antioxidants / chemistry*
  • Antioxidants / pharmacology
  • Biocompatible Materials / chemistry*
  • Biocompatible Materials / pharmacology
  • Coal*
  • Graphite / chemistry*
  • Graphite / pharmacology
  • Humans
  • Oxidation-Reduction
  • Polyethylene Glycols / chemistry
  • Quantum Dots / chemistry
  • Superoxide Dismutase / chemistry

Substances

  • Antioxidants
  • Biocompatible Materials
  • Coal
  • Polyethylene Glycols
  • Graphite
  • Superoxide Dismutase
  • polyethylene glycol 1000