Clinical and laboratory profiles of children with severe chikungunya infection

Rev Soc Bras Med Trop. 2019 Apr 11:52:e20180232. doi: 10.1590/0037-8682-0232-2018.

Abstract

Introduction: Chikungunya infection presents with distinct clinical features depending on the patient age group.

Methods: Medical records of children with positive IgM for the chikungunya virus who were hospitalized in a pediatric ward in Fortaleza, Ceará, Brazil were analyzed.

Results: Fourteen children with a median age of 4 months (36 days to 15 years) were included. All patients presented with fever persisting for an average of 5 days. The joints were involved in 6 (42.8%) children, and 8 (57.1%) children presented with bullous rash.

Conclusions: Systemic involvement and atypical clinical manifestations characterize severe forms of chikungunya infection in children.

MeSH terms

  • Adolescent
  • Chikungunya Fever* / blood
  • Chikungunya Fever* / complications
  • Chikungunya Fever* / diagnosis
  • Child
  • Child, Preschool
  • Female
  • Hospitalization
  • Humans
  • Infant
  • Male
  • Severity of Illness Index