Nanoparticles in dermatologic surgery

J Am Acad Dermatol. 2020 Oct;83(4):1144-1149. doi: 10.1016/j.jaad.2019.04.020. Epub 2019 Apr 13.

Abstract

Nanotechnology is an emerging branch of science that involves the engineering of functional systems on the nanoscale (1-100 nm). Nanotechnology has been used in biomedical and therapeutic agents with the aim of providing novel treatment solutions where small molecule size may be beneficial for modulation of biologic function. Recent investigation in nanomedicine has become increasingly important to cutaneous pathophysiology, such as functional designs directed towards skin cancers and wound healing. This review outlines the application of nanoparticles relevant to dermatologic surgery.

Keywords: drug delivery; keratinocyte carcinoma; melanoma; nanoparticles; nanotechnology; surgery.

Publication types

  • Review

MeSH terms

  • Chitosan / administration & dosage
  • Chitosan / therapeutic use
  • Dendrimers / administration & dosage
  • Dendrimers / therapeutic use
  • Dermatologic Surgical Procedures*
  • Drug Carriers / therapeutic use*
  • Drug Evaluation, Preclinical
  • Fullerenes / administration & dosage
  • Fullerenes / therapeutic use
  • Humans
  • Liposomes / administration & dosage
  • Multicenter Studies as Topic
  • Nanoparticles / therapeutic use*
  • Nitric Oxide / administration & dosage
  • Nitric Oxide / therapeutic use
  • Photosensitizing Agents / administration & dosage
  • Photosensitizing Agents / therapeutic use
  • Randomized Controlled Trials as Topic
  • Skin Neoplasms / drug therapy
  • Skin Neoplasms / surgery
  • Tissue Adhesives / administration & dosage
  • Virosomes / administration & dosage
  • Wound Healing / drug effects

Substances

  • Dendrimers
  • Drug Carriers
  • Fullerenes
  • Liposomes
  • Photosensitizing Agents
  • Tissue Adhesives
  • Virosomes
  • Nitric Oxide
  • Chitosan