[Cutaneous Adverse Drug Reaction Caused by Antiepileptic Drug]

Brain Nerve. 2019 Apr;71(4):401-406. doi: 10.11477/mf.1416201284.
[Article in Japanese]

Abstract

Stevens-Johnson syndrome (SJS), toxic epidermal necrolysis (TEN), and drug induced hypersensitivity syndrome (DIHS) are severe cutaneous adverse reactions, which can be life-threatening and lead to severe sequelae. Antiepileptic drugs frequently cause severe adverse reactions in the form of. It is important to understand the characteristics of each disease and attempt at early diagnosis.

MeSH terms

  • Anticonvulsants / adverse effects*
  • Drug Hypersensitivity / diagnosis*
  • Drug Hypersensitivity / pathology
  • Humans
  • Skin / pathology
  • Stevens-Johnson Syndrome / diagnosis*
  • Stevens-Johnson Syndrome / pathology

Substances

  • Anticonvulsants