Weight loss probiotic supplementation effect in overweight and obesity subjects: A review

Clin Nutr. 2020 Mar;39(3):694-704. doi: 10.1016/j.clnu.2019.03.034. Epub 2019 Apr 3.

Abstract

Obese individuals present adverse changes in the diversity and composition of the gut microbiota, leading to alterations in energy balance, lipid metabolism, endocrine disturbances, and low-grade chronic systemic inflammation increases. Probiotic supplementation appears to change gut microbiota by decrease gut permeability, inflammation, and metabolic disorders, creating a promising environment to weight loss. This revision resumes the main findings of probiotic supplementation and weight loss that contributed to building the current background linking changes in gut microbiota profile and with obesity.

Keywords: Gut microbiota; Obesity; Probiotics; Weight loss.

Publication types

  • Review

MeSH terms

  • Body Mass Index
  • Dietary Supplements*
  • Female
  • Humans
  • Male
  • Obesity / drug therapy
  • Overweight / drug therapy*
  • Probiotics / pharmacology*
  • Weight Loss / drug effects*