Osteoporosis Circumscripta on 68Ga-DOTATATE PET CT

Clin Nucl Med. 2019 Jun;44(6):e404-e405. doi: 10.1097/RLU.0000000000002567.

Abstract

Incidental findings on PET CT studies are common. The distribution of Ga-DOTATATE is dependent on cell surface expression of somatostatin receptors, which may be pathologic or physiologic. Osteoporosis circumscripta is the early lytic phase of Paget disease associated with well-defined osteopenia, most commonly seen within the skull on imaging. The appearance has been well demonstrated on Tc HDP/MDP bone scans. Here, we present the case of a 76-year-old man with a small bowel carcinoid tumor who underwent staging imaging with Ga-DOTATATE PET CT with the incidental finding of osteoporosis circumscripta.

Publication types

  • Case Reports

MeSH terms

  • Aged
  • Carcinoid Tumor / pathology
  • Humans
  • Incidental Findings*
  • Intestinal Neoplasms / pathology
  • Male
  • Neoplasm Staging
  • Organometallic Compounds*
  • Osteitis Deformans / complications
  • Osteitis Deformans / diagnostic imaging*
  • Osteitis Deformans / pathology
  • Positron Emission Tomography Computed Tomography*

Substances

  • Organometallic Compounds
  • gallium Ga 68 dotatate

Supplementary concepts

  • Carcinoid Tumors, Intestinal