[Infected hepatic cyst in ADPKD patient in peritoneal dialysis]

G Ital Nefrol. 2019 Apr;36(2):2019-vol2.
[Article in Italian]

Abstract

Renal and hepatic cysts infections are among the most important infectious complications of ADPKD and often require hospitalization. Liver cysts are even more complex than renal cysts and their diagnosis and treatment are quite controversial. We report the case of a 58-year-old patient with ADPKD undergoing peritoneal dialysis treatment. He presented fever and severe asthenia and was diagnosed with a hepatic cyst infection. Given the presence of the peritoneal catheter, and in order to facilitate the targeted treatment of the infection, we administered antibiotics (ceftazidime and teicoplanin) in the bags used for peritoneal dialysis exchanges for 4 weeks, obtaining the complete disappearance of symptoms and laboratory and ultrasound alterations. Intraperitoneal antibiotics administration in the treatment of infected hepatic cysts represents an effective and safe therapeutic alternative, never described in literature so far.

Keywords: ADPKD; ESRD; infected hepatic cyst; peritoneal dialysis.

Publication types

  • Case Reports

MeSH terms

  • Anti-Bacterial Agents / administration & dosage
  • Bacterial Infections / complications*
  • Bacterial Infections / diagnostic imaging
  • Bacterial Infections / drug therapy
  • Ceftazidime / administration & dosage
  • Cysts / diagnostic imaging
  • Cysts / drug therapy
  • Cysts / etiology*
  • Humans
  • Infusions, Parenteral
  • Liver Diseases / diagnostic imaging
  • Liver Diseases / drug therapy
  • Liver Diseases / etiology*
  • Male
  • Middle Aged
  • Polycystic Kidney, Autosomal Dominant / complications*
  • Renal Dialysis*
  • Renal Insufficiency, Chronic / therapy
  • Teicoplanin / administration & dosage

Substances

  • Anti-Bacterial Agents
  • Teicoplanin
  • Ceftazidime