Reinforcing osteopontin as a marker of central nervous system relapse in paediatric B-cell acute lymphoblastic leukaemia: SPP1 splice variant 3 in the spotlight

Br J Haematol. 2019 Aug;186(4):e88-e91. doi: 10.1111/bjh.15917. Epub 2019 Apr 13.

Authors

Júlio C Santoro¹, Ana C S F Bastos², Etel R P Gimba^{2

3}, Mariana Emerenciano¹

Affiliations

¹ Division of Clinical Research, Research Centre, Instituto Nacional de Câncer-INCA, Rio de Janeiro, RJ, Brazil.
² Program of Cellular and Molecular Oncobiology, Research Centre, Instituto Nacional de Câncer-INCA, Rio de Janeiro, RJ, Brazil.
³ Department of Natural Sciences, Universidade Federal Fluminense, Rio das Ostras, RJ, Brazil.

PMID: 30980383
DOI: 10.1111/bjh.15917

No abstract available

Keywords: B-cell precursor acute lymphoblastic leukaemia; chemoresistance; osteopontin.

Publication types

Letter
Research Support, Non-U.S. Gov't
Comment

MeSH terms

B-Lymphocytes
Burkitt Lymphoma*
Child
Humans
Neoplasm Recurrence, Local
Osteopontin
Precursor Cell Lymphoblastic Leukemia-Lymphoma*

Substances

SPP1 protein, human
Osteopontin