Recurrent Aphthous Stomatitis Caused by Cytomegalovirus, Herpes Simplex Virus, and Candida Species in a Kidney Transplant Recipient: A Case Report

Transplant Proc. 2019 Apr;51(3):993-997. doi: 10.1016/j.transproceed.2019.01.058. Epub 2019 Jan 26.

Abstract

Recipients of organ transplants are immunosuppressed and at high risk of oral infection. Oral diseases are often neglected compared with infections of other organs that typically confer higher morbidity. However, severe local symptoms hinder oral intake, decrease quality of life, and are sometimes lethal. Here we describe a case of a 57-year-old woman who developed recurrent aphthous stomatitis after kidney transplantation; the cause of the infection was complex and included cytomegalovirus, herpes simplex virus, and Candida species. Since misdiagnosis of oral diseases impairs patient quality of life and increases morbidity, clinicians should be aware of possible etiologies of oral infections in renal transplant recipients.

Publication types

  • Case Reports

MeSH terms

  • Candida*
  • Candidiasis / complications
  • Candidiasis / microbiology
  • Cytomegalovirus Infections / complications
  • Cytomegalovirus Infections / virology
  • Cytomegalovirus*
  • Female
  • Herpes Simplex / complications
  • Herpes Simplex / virology
  • Humans
  • Kidney Transplantation / adverse effects*
  • Middle Aged
  • Simplexvirus*
  • Stomatitis, Aphthous / diagnosis
  • Stomatitis, Aphthous / etiology*
  • Transplant Recipients*