Biomedical Applications of Biodegradable Polyesters

Iman Manavitehrani; Ali Fathi; Hesham Badr; Sean Daly; Ali Negahi Shirazi; Fariba Dehghani

doi:10.3390/polym8010020

Biomedical Applications of Biodegradable Polyesters

Polymers (Basel). 2016 Jan 16;8(1):20. doi: 10.3390/polym8010020.

Authors

Iman Manavitehrani¹, Ali Fathi², Hesham Badr³, Sean Daly⁴, Ali Negahi Shirazi⁵, Fariba Dehghani⁶

Affiliations

¹ School of Chemical and Biomolecular Engineering, University of Sydney, NSW 2006, Australia. iman6901@uni.sydney.edu.au.
² School of Chemical and Biomolecular Engineering, University of Sydney, NSW 2006, Australia. ali.fathi@sydney.edu.au.
³ School of Chemical and Biomolecular Engineering, University of Sydney, NSW 2006, Australia. hbad9313@uni.sydney.edu.au.
⁴ School of Chemical and Biomolecular Engineering, University of Sydney, NSW 2006, Australia. sean.daly@sydney.edu.au.
⁵ School of Chemical and Biomolecular Engineering, University of Sydney, NSW 2006, Australia. ali.negahi@sydney.edu.au.
⁶ School of Chemical and Biomolecular Engineering, University of Sydney, NSW 2006, Australia. fariba.dehghani@sydney.edu.au.

Abstract

The focus in the field of biomedical engineering has shifted in recent years to biodegradable polymers and, in particular, polyesters. Dozens of polyester-based medical devices are commercially available, and every year more are introduced to the market. The mechanical performance and wide range of biodegradation properties of this class of polymers allow for high degrees of selectivity for targeted clinical applications. Recent research endeavors to expand the application of polymers have been driven by a need to target the general hydrophobic nature of polyesters and their limited cell motif sites. This review provides a comprehensive investigation into advanced strategies to modify polyesters and their clinical potential for future biomedical applications.

Keywords: biodegradable; medical applications; polyesters; tissue engineering.

Publication types

Review