Intrinsically Disordered Proteins in Chronic Diseases

Prakash Kulkarni; Vladimir N Uversky

doi:10.3390/biom9040147

Intrinsically Disordered Proteins in Chronic Diseases

Biomolecules. 2019 Apr 11;9(4):147. doi: 10.3390/biom9040147.

Authors

Prakash Kulkarni¹, Vladimir N Uversky^{2

3}

Affiliations

¹ Department of Medical Oncology and Therapeutics Research, City of Hope National Medical Center, Duarte, CA 91010, USA. pkulkarni@coh.org.
² Department of Molecular Medicine, Morsani College of Medicine, University of South Florida, Tampa, FL 33612, USA. vuversky@health.usf.edu.
³ Laboratory of New methods in Biology, Institute for Biological Instrumentation, Russian Academy of Sciences, 142290 Pushchino, Moscow Region, Russia. vuversky@health.usf.edu.

Abstract

t is now increasingly evident that a large fraction of the human proteome comprises proteins that, under physiological conditions, lack fixed, ordered 3D structures as a whole or have segments that are not likely to form a defined 3D structure [...].

Publication types

Editorial
Introductory Journal Article

MeSH terms

Animals
Chronic Disease*
Humans
Intrinsically Disordered Proteins / chemistry
Intrinsically Disordered Proteins / genetics
Intrinsically Disordered Proteins / metabolism*

Substances

Intrinsically Disordered Proteins