Bordetella parapertussis Bacteremia: Clinical Expression and Bacterial Genomics

Julie Toubiana; Saba Azarnoush; Valérie Bouchez; Annie Landier; Sophie Guillot; Soraya Matczak; Stéphane Bonacorsi; Sylvain Brisse

doi:10.1093/ofid/ofz122

Bordetella parapertussis Bacteremia: Clinical Expression and Bacterial Genomics

Open Forum Infect Dis. 2019 Mar 7;6(4):ofz122. doi: 10.1093/ofid/ofz122. eCollection 2019 Apr.

Authors

Julie Toubiana^{1

2

3}, Saba Azarnoush⁴, Valérie Bouchez¹, Annie Landier¹, Sophie Guillot¹, Soraya Matczak³, Stéphane Bonacorsi⁵, Sylvain Brisse^{1

2}

Affiliations

¹ Institut Pasteur, Biodiversity and Epidemiology of Bacterial Pathogens, Paris, France.
² National Reference Center for Whooping Cough and Other Bordetella Infections, Paris, France.
³ Department of General Pediatrics and Pediatric Infectious Diseases, Necker-Enfants Malades Hospital, APHP, Paris, France.
⁴ Department of Hematology, Robert Debré Hospital, APHP, Paris, France.
⁵ Microbiology Department, Robert Debré Hospital, APHP, Paris, France.

Abstract

Whooping cough's primary etiological agent is Bordetella pertussis. The closely related Bordetella parapertussis rarely causes severe disease. Here we report an unusual case of bacteremia caused by B. parapertussis, review the literature, and characterize the genomic sequence of the bacterial isolate in comparison with B. parapertussis isolates from respiratory infections.

Keywords: Bordetella parapertussis; bacteremia; children; genomics.