One of the Department of Energy's (DOE) highest priorities is the protection of workers, the public and the environment from the conduct of DOE activities. As a self-regulating agency, DOE develops radiation protection policies and orders that integrate national and international consensus standards into requirements that enable it to complete its diverse missions safely and effectively. DOE leadership is unequivocally committed to the well-being of its workforce involved in carrying out its mission. This commitment helps the Department identify and implement viable, safe, and cost-effective methods to protect its workers who deal with radioactive materials and hazardous substances. This paper provides information on a number of significant ongoing initiatives examining health effects associated with low-dose ionizing radiation exposure (less than 100 mSv), and a list of DOE policies and standards for protection of its workers, the public, and the environment.