Feline Panleukopenia: A Re-emergent Disease

Vet Clin North Am Small Anim Pract. 2019 Jul;49(4):651-670. doi: 10.1016/j.cvsm.2019.02.006. Epub 2019 Apr 6.

Abstract

Feline panleukopenia (FPL) is caused by a Carnivore protoparvovirus infection. Feline parvovirus (FPV) causes most cases. When Canine parvovirus 2 (CPV-2) first emerged, it could not replicate in cats. All current CPV variants (CPV-2a-c) can infect cats to cause subclinical disease or FPL. Feline panleukopenia has re-emerged in Australia in shelter cats associated with failure to vaccinate. Parvoviruses can remain latent in mononuclear cells post-infection. Molecular methods such as polymerase chain reaction are used to determine the infecting strain. Current perspectives on causes, epidemiology, diagnosis, treatment, prognostic indicators, and management of outbreaks in shelters are reviewed.

Keywords: Canine; Carnivore protoparvovirus; Enteritis; Feline; Panleukopenia; Parvovirus; Shelter medicine.

Publication types

  • Review

MeSH terms

  • Animals
  • Cats
  • Communicable Diseases, Emerging / transmission
  • Communicable Diseases, Emerging / veterinary*
  • Communicable Diseases, Emerging / virology
  • Feline Panleukopenia / epidemiology*
  • Feline Panleukopenia / pathology
  • Feline Panleukopenia / virology
  • Parvoviridae Infections / epidemiology
  • Parvoviridae Infections / veterinary
  • Parvoviridae Infections / virology
  • Parvovirus, Canine