Simultaneous diagnosis of unilateral retinoblastoma and contralateral optic pathway glioma in a child with neurofibromatosis type 1

Pediatr Hematol Oncol. 2019 Mar;36(2):82-85. doi: 10.1080/08880018.2019.1591550. Epub 2019 Apr 9.

Authors

Anirban Das¹, Priya Ghosh², Lateef Zameer³, Vedam L Ramprasad⁴, Anirban Bhaduri⁵

Affiliations

¹ a Department of Pediatric Hematology/Oncology , Tata Medical Center , Kolkata , India.
² b Department of Radiology , Tata Medical Center , Kolkata , India.
³ c Department of Histopathology , Tata Medical Center , Kolkata , India.
⁴ d Medgenome labs , Bangalore , Karnataka , India.
⁵ e Department of Ophthalmology , The Calcutta Medical Research Institute , Kolkata , India.

PMID: 30963792
DOI: 10.1080/08880018.2019.1591550

No abstract available

Keywords: LGG; NF1; OPG; RB; orbital cellulitis.

Publication types

Case Reports

MeSH terms

Child, Preschool
Codon, Nonsense
Diagnosis, Differential
Exons / genetics
Eye Enucleation
Eye Neoplasms / diagnosis*
Eye Neoplasms / genetics
Eye Neoplasms / surgery
Female
Genes, Retinoblastoma
Genetic Predisposition to Disease
Humans
Mutation, Missense
Neoplasms, Multiple Primary / diagnosis*
Neoplasms, Multiple Primary / genetics
Neoplasms, Multiple Primary / surgery
Neurofibromatosis 1* / diagnosis
Neurofibromatosis 1* / genetics
Optic Nerve Glioma / diagnosis*
Optic Nerve Glioma / genetics
Optic Nerve Glioma / surgery
Optic Nerve Neoplasms / diagnosis*
Optic Nerve Neoplasms / genetics
Optic Nerve Neoplasms / surgery
Orbital Cellulitis / diagnosis
Retinoblastoma / diagnosis*
Retinoblastoma / genetics
Retinoblastoma / surgery
Retinoblastoma Binding Proteins / genetics
Sequence Deletion
Ubiquitin-Protein Ligases / genetics

Substances

Codon, Nonsense
RB1 protein, human
Retinoblastoma Binding Proteins
Ubiquitin-Protein Ligases