Randomized Controlled Trial Comparing the Usefulness of Endoscopic Ultrasound Processor

Hiroki Koda; Kazuya Matsumoto; Yohei Takeda; Takumi Onoyama; Soichiro Kawata; Hiroki Kurumi; Taro Yamashita; Hisashi Noma; Hajime Isomoto

doi:10.33160/yam.2019.03.013

Randomized Controlled Trial Comparing the Usefulness of Endoscopic Ultrasound Processor

Yonago Acta Med. 2019 Mar 28;62(1):94-99. doi: 10.33160/yam.2019.03.013. eCollection 2019 Mar.

Authors

Hiroki Koda¹, Kazuya Matsumoto¹, Yohei Takeda¹, Takumi Onoyama¹, Soichiro Kawata¹, Hiroki Kurumi¹, Taro Yamashita¹, Hisashi Noma², Hajime Isomoto¹

Affiliations

¹ Department of Gastroenterology, Tottori University Hospital, Yonago 683-8504, Japan.
² †Department of Data Science, The Institute of Statistical Mathematics, Tachikawa 190-8562, Japan.

Abstract

Background: Although endoscopic ultrasonography (EUS) is a useful tool for diagnosing pancreatobiliary diseases, not many facilities perform this technique as it is difficult to master. Currently, two new EUS systems exist: EU-ME2/GF-UCT260, manufactured by Olympus, and SU-1/EG-580UT, manufactured by Fujifilm. Some reports have compared new EUS models to older versions, but the operability and image quality of these two latest systems have not been compared. Our study aimed to compare the usefulness of these two types of EUS.

Methods: Forty consecutive patients were recruited and randomized in a two-arm clinical trial; Arm 1: EU-ME2/GF-UCT260 was used only for observation and SU-1/EG-580UT for EUS-fine needle aspiration (FNA); Arm 2: SU-1/EG-580UT was used only for observation and EU-ME2/GF-UCT260 for EUS-FNA. Using a crossover design, we evaluated image findings, ease of scope insertion, and visibility of the gastrointestinal (GI) tract. Each procedure was scored using a 5-point scale (Clinical Trial ID: UMIN000031373).

Results: SU-1/EG-580UT was significantly better in terms of lesion-delineating capacity: lesion border (P < 0.001), internal echo (P < 0.001). Significantly easier scope insertion was observed with SU-1/EG-580UT with respect to any insertion into the piriform recess (P = 0.018), the pylorus ring (P < 0.001), and the superior duodenal angle (P < 0.001). Visibility during gastrointestinal observation was also significantly better with the SU-1/EG-580UT (P < 0.001) than with the EU-ME2/GF-UCT260.

Conclusion: SU-1/EG-580UT EUS demonstrated superior performance during ultrasonic endoscopic GI observation, operability, and ultrasonic image quality. The result of the superior ultrasound imaging quality of SU-1/EG-580UT EUS will aid in the identification of small pancreatic malignancies with unclear borders and prove useful in evaluating mural nodules of IPMN in detail. These findings could result in an increased use of EUS and improve identification and prognosis of patients with pancreatobiliary diseases.

Keywords: EG-580UT; EU-ME2; GF-UCT260; SU-1; endoscopic ultrasonography.