An adenine base editor with expanded targeting scope using SpCas9-NGv1 in rice

Plant Biotechnol J. 2019 Aug;17(8):1476-1478. doi: 10.1111/pbi.13120. Epub 2019 Apr 30.

Authors

Katsuya Negishi¹, Hidetaka Kaya^{1

2}, Kiyomi Abe¹, Naho Hara¹, Hiroaki Saika¹, Seiichi Toki^{1

3

4}

Affiliations

¹ Plant Genome Engineering Research Unit, Institute of Agrobiological Sciences, National Agriculture and Food Research Organization, Tsukuba, Ibaraki, Japan.
² Graduate School of Agriculture, Ehime University, Matsuyama, Ehime, Japan.
³ Graduate School of Nanobioscience, Yokohama City University, Yokohama, Kanagawa, Japan.
⁴ Kihara Institute for Biological Research, Yokohama City University, Yokohama, Kanagawa, Japan.

No abstract available

Keywords: Oryza sativa; CRISPR/Cas9; SpCas9-NG; adenine base editor; genome editing; protospacer adjacent motif.

Publication types

Letter
Research Support, Non-U.S. Gov't

MeSH terms

Adenine*
CRISPR-Associated Protein 9 / genetics*
CRISPR-Cas Systems*
Gene Editing*
Oryza / genetics*

Substances

CRISPR-Associated Protein 9
Adenine