Sclerosing Tumors of the Gastrointestinal Tract: A Systematic Approach

Int J Surg Pathol. 2019 Aug;27(5):468-476. doi: 10.1177/1066896919840431. Epub 2019 Apr 8.

Abstract

Some lesions in the gastrointestinal tract have a propensity for sclerosis such that it may mask the actual true nature of the lesion. The purpose of this review is to highlight those lesions of the gastrointestinal tract that can be attended by sclerosis. The sclerosis can mask the cellularity of the lesion; hence, knowledge of the key lesions that are known to have sclerosis will be aid the diagnostic pathologist.

Keywords: GIST; gastrointestinal tract; neuroendocrine tumors; schwannoma; sclerosis.

Publication types

  • Review

MeSH terms

  • Biomarkers, Tumor / analysis
  • Diagnosis, Differential
  • Gastrointestinal Neoplasms / diagnosis*
  • Gastrointestinal Neoplasms / pathology
  • Gastrointestinal Stromal Tumors / diagnosis*
  • Gastrointestinal Stromal Tumors / pathology
  • Gastrointestinal Tract / pathology*
  • Humans
  • Neuroendocrine Tumors / diagnosis*
  • Neuroendocrine Tumors / pathology
  • Sclerosis / diagnosis*
  • Sclerosis / pathology

Substances

  • Biomarkers, Tumor