Feasibility of automated fetal fractional shortening measurement with two-dimensional tracking and construction of a reference range for normal fetuses

J Med Ultrason (2001). 2019 Oct;46(4):467-472. doi: 10.1007/s10396-019-00942-6. Epub 2019 Apr 5.

Abstract

Purpose: To assess the feasibility of an automated fractional shortening (Auto FS) measurement method using two-dimensional tracking and to construct a reference range for normal fetuses.

Methods: This study was conducted from May 2017 to March 2018. First, cardiac motion in the four-chamber view was recorded in the B-mode. Subsequently, the region of interest was set on the edge of the ventricular septum or ventricular muscle at a point one-third away from the atrioventricular valve toward the cardiac apex. Tracking was automatically performed. Values measured between the ventricular septum and right ventricle were defined as R-Auto FS, whereas those measured between the ventricular septum and left ventricle were defined as L-Auto FS. Those on each ventricular muscle were defined as Combined-Auto FS.

Results: Data were obtained from 131 singleton fetuses. R-Auto FS significantly decreased with an increase in the number of gestational weeks, and L-Auto FS and Combined-Auto FS showed the same tendency (Spearman's correlation analysis: p = - .528, p = - .351, and p = - .636, respectively).

Conclusion: We succeeded in defining a reference Auto FS value for normal singleton pregnancies. Auto FS was negatively correlated with gestational age. This novel technique can assess fetal heart contractility.

Keywords: Auto FS; Fetal cardiac function; Fractional shortening; Two-dimensional tracking method.

MeSH terms

  • Adolescent
  • Adult
  • Echocardiography / methods*
  • Feasibility Studies
  • Female
  • Fetal Heart / diagnostic imaging
  • Fetal Heart / physiology*
  • Humans
  • Image Processing, Computer-Assisted / methods*
  • Pregnancy
  • Prospective Studies
  • Reference Values
  • Ultrasonography, Prenatal / methods*
  • Young Adult