Extensive meningeal enhancement in acute central nervous system Lyme: Case series and review of literature

Abstract

Introduction: Clinical presentation of the central nervous system Lyme disease is nonspecific and therefore brain imaging and disease-specific serological testing is generally pursued to assist with diagnosis. Brain imaging findings are, however, rare and often unspecific.

Case description: In the current report, we are presenting a rare magnetic resonance imaging (MRI) finding of extensive meningeal enhancement in two patients with acute Lyme disease.

Discussion: We discussed clinical implications and reviewed the relevant literature.

Keywords: CNS Lyme; Magnetic resonance imaging; Meningeal enhancement.