Phacolytic glaucoma: A nearly forgotten entity

Eur J Ophthalmol. 2020 Sep;30(5):NP32-NP35. doi: 10.1177/1120672119841972. Epub 2019 Apr 5.

Abstract

Purpose: To report a case of phacolytic glaucoma with rupture of anterior lens capsule in a case of hypermature cataract.

Methods: Case report and literature review.

Results: An 80-year-old woman presented with cloudiness and pain in the left eye for 1 day. The patient had visual acuity limited to perception of light with raised intraocular pressure of 70 mm Hg. Careful slit-lamp evaluation revealed corneal epithelial edema in superior quadrant and a deep and turbid anterior chamber. Ultrasound biomicroscopy confirmed the presence of a deep anterior chamber, a hypermature cataractous nucleus with lax capsular bag, and ruptured anterior lens capsule. The patient underwent extracapsular cataract extraction. Cytological examination of the lenticular fluid revealed the presence of lens protein-laden macrophages. Post-operatively, the patient had best-corrected visual acuity of 6/60 with advanced glaucomatous optic neuropathy.

Conclusion: Phacolytic glaucoma can present with a cloudy cornea and a turbid anterior chamber mimicking endophthalmitis. Careful examination and ancillary investigations including ultrasound biomicroscopy was helpful in making an accurate diagnosis.

Keywords: Phacolytic glaucoma; hypermature cataract; lens-induced glaucoma; ultrasound biomicroscopy.

Publication types

  • Case Reports
  • Review

MeSH terms

  • Aged, 80 and over
  • Anterior Capsule of the Lens / diagnostic imaging
  • Anterior Capsule of the Lens / pathology
  • Anterior Chamber / diagnostic imaging
  • Anterior Chamber / pathology
  • Antihypertensive Agents / therapeutic use
  • Cataract / complications*
  • Cataract Extraction*
  • Corneal Diseases / etiology
  • Female
  • Glaucoma / diagnostic imaging
  • Glaucoma / drug therapy
  • Glaucoma / etiology*
  • Humans
  • Intraocular Pressure
  • Lens Nucleus, Crystalline / diagnostic imaging
  • Lens Nucleus, Crystalline / pathology*
  • Microscopy, Acoustic
  • Ocular Hypertension / diagnostic imaging
  • Ocular Hypertension / drug therapy
  • Ocular Hypertension / etiology
  • Tonometry, Ocular
  • Visual Acuity / physiology

Substances

  • Antihypertensive Agents