A total of 1,397 rodents of 7 different species were collected in the major vegetative zones of Senegal. Organ pools from rodents were inoculated into suckling-mice. Thirty-five viral strains, representing 5 viruses, were isolated. The 5 viral types recovered in the present survey comprise: Bandia (23 strains), Saboya (7), Salanga (3), Gabek Forest (1) and a new poxvirus (AnD 42332) for which the name of Fadiga is proposed. This virus was isolated from a Mastomys sp collected in eastern Senegal. Antigenic relations were established by complement fixation test with Salanga virus; its distinctness was determined by neutralisation test. Our data are discussed with compiled informations on the current status of rodent viral isolations in West and Central Africa.