Taming the "Black Dog" by Light: A Retina-Habenula Circuit Mechanism Unveiled

Yiyan Dong; Hailan Hu

doi:10.1016/j.neuron.2019.02.033

Taming the "Black Dog" by Light: A Retina-Habenula Circuit Mechanism Unveiled

Neuron. 2019 Apr 3;102(1):3-5. doi: 10.1016/j.neuron.2019.02.033.

Authors

Yiyan Dong¹, Hailan Hu²

Affiliations

¹ Center for Neuroscience and Department of Psychiatry of First Affiliated Hospital, Zhejiang University School of Medicine, Hangzhou 310000, China; Interdisciplinary Institute of Neuroscience and Technology, Qiushi Academy for Advanced Studies, Zhejiang University, Hangzhou 310058, China; NHC and CAMS Key Laboratory of Medical Neurobiology, Mental Health Center, Zhejiang University, Hangzhou 310058, China.
² Center for Neuroscience and Department of Psychiatry of First Affiliated Hospital, Zhejiang University School of Medicine, Hangzhou 310000, China; Interdisciplinary Institute of Neuroscience and Technology, Qiushi Academy for Advanced Studies, Zhejiang University, Hangzhou 310058, China; NHC and CAMS Key Laboratory of Medical Neurobiology, Mental Health Center, Zhejiang University, Hangzhou 310058, China. Electronic address: huhailan@zju.edu.cn.

PMID: 30946824
DOI: 10.1016/j.neuron.2019.02.033

Abstract

Light exerts powerful effects on mood and has been used for the therapeutic treatment of depression. In this issue of Neuron, Huang et al. (2019) identify a visual pathway linked to the lateral habenula mediating the antidepressant effects of light.

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MeSH terms

Animals
Antidepressive Agents
Depression
Dogs
Habenula*
Phototherapy
Retina

Substances

Antidepressive Agents