Clinicopathological factors influencing the prognosis of cervical cancer

J BUON. 2019 Jan-Feb;24(1):291-295.

Abstract

Purpose: This research was designed to analyze the clinicopathological factors affecting the prognosis of cervical cancer.

Methods: The clinical and follow-up data of 79 patients with cervical cancer were retrospectively analyzed by univariate and multivariate analysis. The 5-year overall survival rate was 74% for all patients.

Results: Univariate analysis showed that the 5-year survival rate of patients with clinical stage I-IIA cervical cancer was higher than that of IIB-IV. The 5-year survival rates were higher in patients without parametrial invasion than those with parametrial invasion; higher in patients without vascular invasion than those with vascular invasion; and higher in patients without lymph node metastasis than those with lymph node metastasis. Multivariate analysis showed that vascular invasion, lymph node metastasis, and clinical stage were independent predictors of overall survival.

Conclusion: Vascular invasion, lymph node metastasis, and clinical stage are independent predictors for the prognosis of cervical cancer.

MeSH terms

  • Adenocarcinoma / mortality
  • Adenocarcinoma / secondary*
  • Adenocarcinoma / therapy
  • Adult
  • Aged
  • Carcinoma, Squamous Cell / mortality
  • Carcinoma, Squamous Cell / secondary*
  • Carcinoma, Squamous Cell / therapy
  • Combined Modality Therapy
  • Female
  • Follow-Up Studies
  • Humans
  • Lymphatic Metastasis
  • Middle Aged
  • Neoplasm Invasiveness
  • Neoplasm Staging
  • Retrospective Studies
  • Risk Factors
  • Survival Rate
  • Uterine Cervical Neoplasms / mortality
  • Uterine Cervical Neoplasms / pathology*
  • Uterine Cervical Neoplasms / therapy