Long-Term Results of Endovascular Treatment of Chronic Iliofemoral Venous Obstructive Lesions

Vasc Endovascular Surg. 2019 Jul;53(5):373-378. doi: 10.1177/1538574419839256. Epub 2019 Apr 1.

Abstract

Objective: To evaluate the long-term results in endovascular treatment of iliofemoral venous obstructive lesions.

Methods: From January 2009 to March 2017, 75 patients were admitted for endovascular treatment of chronic obstructive lesions of the iliofemoral veins. Of these, 60 patients underwent stenting of postthrombotic obstructions and 15 patients stenting of nonthrombotic obstructive lesions of the iliac veins (May-Thurner syndrome in 11, for tumor-induced compression and cicatricial stenosis in 4). Dynamic control of stent patency was carried out by means of duplex ultrasound. Efficacy of endovascular intervention was evaluated by measuring the venous pressure gradient and malleolar circumference. The clinical result was determined by the Venous Clinical Severity Score (VCSS).

Results: Technical success of endovascular intervention in postthrombotic occlusions of iliac vein was 92% and in nonthrombotic iliac vein lesions was 100%. Cumulative primary and secondary patency in postthrombotic lesions at 60 months amounted to 72% and 81%, respectively, in nonthrombotic lesions to 85% (primary patency). Reinterventions were successfully performed in 6 patients including catheter-directed thrombolysis (3 patients) and stenting (3 patients). The mean VCSS score fell from 14.2 (4.2) to 7.5 (2.6; P < .001). The quality of life was improved; its mean score decreased from 62.6 (18.7) to 48.7 (12.8; P < .01).

Conclusion: Endovascular angioplasty and stenting for obstructive lesions of the iliofemoral veins is a minimally invasive, safe, and highly effective method of treatment, which is confirmed by a significant improvement of the limb's condition and good long-term results of patency of the restored venous segments.

Keywords: computed tomographic venography; contrast venography; duplex ultrasound; obstructive lesions of iliofemoral veins; venous stenting.

MeSH terms

  • Adolescent
  • Adult
  • Angioplasty, Balloon* / adverse effects
  • Angioplasty, Balloon* / instrumentation
  • Blood Flow Velocity
  • Chronic Disease
  • Computed Tomography Angiography
  • Female
  • Femoral Vein / diagnostic imaging
  • Femoral Vein / physiopathology
  • Femoral Vein / surgery*
  • Humans
  • Iliac Vein / diagnostic imaging
  • Iliac Vein / physiopathology
  • Iliac Vein / surgery*
  • Male
  • Middle Aged
  • Phlebography / methods
  • Postthrombotic Syndrome / diagnostic imaging
  • Postthrombotic Syndrome / physiopathology
  • Postthrombotic Syndrome / surgery*
  • Risk Factors
  • Stents
  • Time Factors
  • Treatment Outcome
  • Ultrasonography, Doppler, Color
  • Vascular Patency
  • Venous Insufficiency / diagnostic imaging
  • Venous Insufficiency / physiopathology
  • Venous Insufficiency / surgery*
  • Venous Pressure
  • Venous Thrombosis / diagnostic imaging
  • Venous Thrombosis / physiopathology
  • Venous Thrombosis / surgery*
  • Young Adult