Abstract
Clinical and morphological features of urinary bladder transitional carcinoma pathomorphosis after regional endolymphic polychemotherapy were studied to estimate the criteria of treatment efficiency and prognosis. Quantitative assessment of chemosensitive and chemoresistant tumours is given. The degree of cataplasia, growth character, the amount of stroma, blood supply and intensity of mononuclear infiltration predetermine the stage of pathomorphosis, efficiency of bladder cancer treatment. Studies of stromal immunomorphology, features of blood supply, mechanisms of neoplastic angiogenesis provide better understanding of biological nature of tumours, improve prognosis and choice of treatment.
Publication types
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Comparative Study
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English Abstract
MeSH terms
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Antineoplastic Combined Chemotherapy Protocols / administration & dosage*
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Carcinoma, Transitional Cell / blood supply
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Carcinoma, Transitional Cell / drug therapy
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Carcinoma, Transitional Cell / pathology*
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Chemotherapy, Cancer, Regional Perfusion
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Cyclophosphamide / administration & dosage
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Drug Evaluation
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Drug Resistance
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Fluorouracil / administration & dosage
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Humans
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Injections, Intralymphatic
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Middle Aged
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Necrosis
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Neoplasm Metastasis
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Thiotepa / administration & dosage
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Urinary Bladder / pathology
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Urinary Bladder Neoplasms / blood supply
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Urinary Bladder Neoplasms / drug therapy
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Urinary Bladder Neoplasms / pathology*
Substances
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Cyclophosphamide
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Thiotepa
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Fluorouracil