Identification of a novel HLA-DPB1, HLA-DPB1*687:01, in an Italian renal transplant candidate

HLA. 2019 Jul;94(1):89-90. doi: 10.1111/tan.13538. Epub 2019 Apr 10.

Abstract

Two adjacent nucleotide substitutions in exon 2 characterize the novel class II HLA-DPB1*687:01 allele.

Keywords: HLA-DPB1*687:01; novel allele; sequence-based typing.

MeSH terms

  • Alleles
  • Amino Acid Substitution
  • Base Sequence
  • Exons*
  • HLA-DP beta-Chains / genetics*
  • Histocompatibility Testing / methods*
  • Humans
  • Italy
  • Kidney Transplantation*
  • Male
  • Polymorphism, Single Nucleotide*
  • Sequence Analysis, DNA / methods*
  • Sequence Homology

Substances

  • HLA-DP beta-Chains
  • HLA-DPB1 antigen