Can Laccase-Assisted Processing Conditions Influence the Structure of the Reaction Products?

Trends Biotechnol. 2019 Jul;37(7):683-686. doi: 10.1016/j.tibtech.2019.03.006. Epub 2019 Mar 27.

Abstract

Laccase is a promiscuous enzyme that catalyzes the polymerization of a wide range of phenolic substrates. Diverse poly(catechol) products can be obtained depending on the reactor employed and modifications of the laccase enzyme. The generation of these different reaction products may be attributed to changes in the geometry of the enzyme active site induced by different environmental conditions.

Keywords: laccase; polymer structure; processing conditions; protein modification.

Publication types

  • Research Support, Non-U.S. Gov't
  • Review

MeSH terms

  • Biopolymers / metabolism*
  • Catalytic Domain
  • Catechols / metabolism*
  • Laccase / chemistry*
  • Laccase / genetics
  • Laccase / metabolism*
  • Protein Conformation
  • Protein Engineering / methods*
  • Substrate Specificity

Substances

  • Biopolymers
  • Catechols
  • Laccase