Tutorial on lipidomics

Anal Chim Acta. 2019 Jul 11:1061:28-41. doi: 10.1016/j.aca.2019.01.043. Epub 2019 Feb 1.

Abstract

The mainstream of lipidomics involves mass spectrometry-based, systematic, and large-scale studies of the structure, composition, and quantity of lipids in biological systems such as organs, cells, and body fluids. As increasingly more researchers in broad fields are beginning to pay attention to and actively learn about the lipidomic technology, some introduction on the topic is needed to help the newcomers to better understand the field. This tutorial seeks to introduce the basic knowledge about lipidomics and to provide readers with some core ideas and the most important approaches for studying the field.

Keywords: Lipidomics; Lipids; Mass spectrometry; Metabolic syndrome; Neurodegenerative diseases; Shotgun lipidomics.

Publication types

  • Review

MeSH terms

  • Computational Biology
  • Humans
  • Lipids / chemistry*
  • Mass Spectrometry

Substances

  • Lipids