Why results from Bayesian statistical analyses of clinical trials with a strong prior and small sample sizes may be misleading The case of the NICHD Neonatal Research Network Late Hypothermia Trial

Acta Paediatr. 2019 Jul;108(7):1190-1191. doi: 10.1111/apa.14800. Epub 2019 Apr 11.

Authors

Lars Walløe¹, Nils Lid Hjort², Marianne Thoresen^{1

3}

Affiliations

¹ Division of Physiology, Institute of Basic Medical Sciences, University of Oslo, Oslo, Norway.
² Division of Statistics and Biostatistics, Department of Mathematics, University of Oslo, Oslo, Norway.
³ Neonatal Neuroscience, Translational Health Sciences, University of Bristol, Bristol, UK.

No abstract available

Publication types

Research Support, Non-U.S. Gov't
Comment

MeSH terms

Bayes Theorem
Humans
Hypothermia*
Hypoxia-Ischemia, Brain*
Infant, Newborn
National Institute of Child Health and Human Development (U.S.)
Sample Size
United States

Grants and funding