Identity-by-Descent Analysis Reveals Susceptibility Loci for Severe Acne in Chinese Han Cohort

Xingyan Yang; Wenjuan Wu; Minsheng Peng; Quankuan Shen; Jiaqi Feng; Wei Lai; Huilan Zhu; Caixia Tu; Xiaorong Quan; Yihong Chen; Lanying Qin; Donglin Li; Li He; Yaping Zhang

doi:10.1016/j.jid.2019.03.1132

Identity-by-Descent Analysis Reveals Susceptibility Loci for Severe Acne in Chinese Han Cohort

J Invest Dermatol. 2019 Sep;139(9):2049-2051.e20. doi: 10.1016/j.jid.2019.03.1132. Epub 2019 Mar 25.

Authors

Xingyan Yang¹, Wenjuan Wu², Minsheng Peng³, Quankuan Shen⁴, Jiaqi Feng², Wei Lai⁵, Huilan Zhu⁶, Caixia Tu⁷, Xiaorong Quan⁸, Yihong Chen⁹, Lanying Qin¹⁰, Donglin Li², Li He¹¹, Yaping Zhang¹²

Affiliations

¹ State Key Laboratory for Conservation and Utilization of Bio-Resources in Yunnan, School of Life Sciences, Yunnan University, Kunming, China.
² Department of Dermatology, First Affiliated Hospital of Kunming Medical University, Institute of Dermatology and Venereology of Yunnan Province, Kunming, China.
³ State Key Laboratory of Genetic Resources and Evolution, Kunming Institute of Zoology, Chinese Academy of Sciences, Kunming, China; Kunming College of Life Science, University of Chinese Academy of Sciences, Kunming, China; KIZ/CUHK Joint Laboratory of Bio-Resources and Molecular Research in Common Diseases, Kunming Institute of Zoology, Chinese Academy of Sciences, Kunming, China.
⁴ State Key Laboratory of Genetic Resources and Evolution, Kunming Institute of Zoology, Chinese Academy of Sciences, Kunming, China; Kunming College of Life Science, University of Chinese Academy of Sciences, Kunming, China.
⁵ Department of Dermatology, The Third Affiliated Hospital of Sun Yat-sen University, Guangzhou, China.
⁶ Guangzhou Institute of Dermatology, Guangzhou, China.
⁷ Department of Dermatology, The Second Affiliated Hospital of Dalian Medical University, Dalian, China.
⁸ Guilin Skin Disease Prevention and Treatment Hospital, Guilin, China.
⁹ Department of Dermatology, Zhangzhou Affiliated Hospital of Fujian Medical University, Zhangzhou, China.
¹⁰ Department of Dermatology, Cangzhou People's Hospital, Cangzhou, China.
¹¹ Department of Dermatology, First Affiliated Hospital of Kunming Medical University, Institute of Dermatology and Venereology of Yunnan Province, Kunming, China. Electronic address: helikm2662@126.com.
¹² State Key Laboratory for Conservation and Utilization of Bio-Resources in Yunnan, School of Life Sciences, Yunnan University, Kunming, China; State Key Laboratory of Genetic Resources and Evolution, Kunming Institute of Zoology, Chinese Academy of Sciences, Kunming, China; Kunming College of Life Science, University of Chinese Academy of Sciences, Kunming, China; KIZ/CUHK Joint Laboratory of Bio-Resources and Molecular Research in Common Diseases, Kunming Institute of Zoology, Chinese Academy of Sciences, Kunming, China. Electronic address: zhangyp@mail.kiz.ac.cn.

PMID: 30922884
DOI: 10.1016/j.jid.2019.03.1132

No abstract available

Publication types

Letter
Research Support, Non-U.S. Gov't

MeSH terms

Acne Vulgaris / diagnosis
Acne Vulgaris / genetics*
Asian People / genetics*
Case-Control Studies
China
Chromosomes, Human, Pair 4 / genetics
Chromosomes, Human, Pair 6 / genetics
Cohort Studies
DNA-Binding Proteins / genetics
Datasets as Topic
Genetic Loci*
Genetic Predisposition to Disease*
Genome-Wide Association Study
Humans
Polymorphism, Single Nucleotide
Severity of Illness Index

Substances

DDB2 protein, human
DNA-Binding Proteins