Acetic acid treatment for toe web infection caused by Pseudomonas Aeruginosa combined with fungal infection: A case series of ten patients

Dermatol Ther. 2019 May;32(3):e12883. doi: 10.1111/dth.12883. Epub 2019 Apr 17.

Abstract

Gram-negative bacterial toe web infection (GNBTWI) caused by Pseudomonas Aeruginosa combined with fungal infection has variety of treatments. However, these treatments have been poorly described in the literature. Our retrospective study describes patients that had been treated in our medical center with acetic acid combined with local antifungal treatment, to evaluate evidences for the appropriateness of this treatment. Ten patients with evidence of GNBTWI caused by Pseudomonas Aeruginosa combined with local fungal infection which have been treated with acetic acid in Emek Medical Center were identified. Eight patients (80%) had a complete response while two patients (20%) showed only a partial response. Side effects were minimal and included temporary stinging sensation. Acetic acid is a relatively cheap ingredient with minimal side effect profile and highly effective outcomes as a treatment for GNBTWI caused by Pseudomonas Aeruginosa and should be considered as an adjuvant treatment.

Keywords: acetic acid; fungal infection; gram negative bacteria; infection; pseudomonas aeruginosa; treatment.

MeSH terms

  • Acetic Acid / therapeutic use*
  • Adult
  • Aged
  • Antifungal Agents / therapeutic use
  • Foot Dermatoses / drug therapy*
  • Humans
  • Male
  • Middle Aged
  • Mycoses / drug therapy*
  • Pseudomonas Infections / drug therapy*
  • Retrospective Studies
  • Toes

Substances

  • Antifungal Agents
  • Acetic Acid