Still Searching for Specialized Ribosomes

Eric S Haag; Jonathan D Dinman

doi:10.1016/j.devcel.2019.03.005

Still Searching for Specialized Ribosomes

Dev Cell. 2019 Mar 25;48(6):744-746. doi: 10.1016/j.devcel.2019.03.005.

Authors

Eric S Haag¹, Jonathan D Dinman²

Affiliations

¹ Department of Biology, University of Maryland, College Park, MD 20742, USA. Electronic address: ehaag@umd.edu.
² Department of Cell Biology and Molecular Genetics, University of Maryland, College Park, MD 20742, USA. Electronic address: dinman@umd.edu.

PMID: 30913404
DOI: 10.1016/j.devcel.2019.03.005

Abstract

Reporting in Developmental Cell, Cenik et al. (2019) show that the maternal ribosome supply is sufficient for C. elegans embryonic development, arguing against tissue-specific specialized ribosomes in this context. Examination of ribosomal requirement with the genetic tool kit presented in Artiles et al. (2019) suggests a checkpoint that prevents uncoordinated growth.

Publication types

Research Support, N.I.H., Extramural
Comment

MeSH terms

Animals
Caenorhabditis elegans*
Ribosomes*

Grants and funding

R01 HL119439/HL/NHLBI NIH HHS/United States